The physical activity is recommended to prevent and to treat several diseases such as obesity, type 2 Diabetes, metabolic syndrome, arterial hypertension, dysplidemia, osteoporosis, chronic obstructive pulmonary disease, depression, reduced functional capacity in elderly population. On the basis of the agreement between the University of Perugia, the Public Health Department of Umbria Region and the Local Hospital Authority, the Healthy Lifestyle Institute promotes a multidisciplinary lifestyle intervention among the population aimed at improving physical and mental health through a structured program of physical activity planned according to the individual diseases. Our actions are towards a healthier lifestyle and the results will be highly dependent on your cooperation.